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Acetylcysteine
acetylcysteine, drug, effects, interactions, side, should, may, doctor, solution, special, use, opening, advice, such, symptoms, mucus, available, nebulizer, common, problems, any, breast, other, breathing, food, hoursBy Talk to the Author.
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Brand Name(s):Mucomyst, Mucosil Drug Class:Decongestant/ cough drug Available OTC?:NoAvailable Generic?:Yes | |
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Available InInhalant solution Why PrescribedTo relieve congestion and make breathing easier in lung conditions associated with the production of large amounts of thick mucus, such as bronchiectasis (irreversible destruction of the bronchial walls), bronchitis, pneumonia, and cystic fibrosis. It may also be used in patients who have undergone tracheostomy (surgical opening in the neck to establish an airway when the throat is obstructed), or who have a collapsed lobe of the lung due to a plug of mucus blocking an airway. How It WorksAcetylcysteine liquefies and thins mucus so that it may be coughed up (or removed with suction if necessary). Range and Frequency3 to 5 ml of 20% solution, or 6 to 10 ml of 10% solution by nebulizer every two to six hours. (The medicine may be inhaled through a face mask, mouthpiece, or via tracheostomy.) Or, 1 to 2 ml of 10% or 20% solution placed directly into the trachea via catheter every hour. The dosage differs from patient to patient; follow your doctor's directions carefully. Onset of EffectWithin one minute. Duration of ActionUp to several hours. Dietary AdviceThis drug should not be taken with meals. Be sure to drink plenty of fluids. StorageBefore opening, store container away from heat and direct light. After opening, store it in the refrigerator, but do not allow it to freeze. Discard the container 96 hours after opening. Missed DoseTake it as soon as you remember. Take the rest of the day's doses at evenly spaced intervals. Stopping the DrugThe decision to stop taking the drug should be made by your doctor. Prolonged UseNo special problems are expected. Over 60No special problems are expected. Driving and Hazardous WorkBe cautious if acetylcysteine makes you drowsy. AlcoholAlcohol intake should be limited. PregnancyThe effects of acetylcysteine on the human fetus have not been documented; consult your doctor or OB/GYN for specific advice if your are pregnant or plan to become pregnant. Breast FeedingIt is not known whether acetylcysteine passes into breast milk; problems have not been documented. Consult your doctor for specific advice before deciding to nurse while using this drug. Infants and ChildrenNo special problems are expected. Special ConcernsBe sure to tell your doctor if you have ever had any unusual or allergic reaction to acetylcysteine, or if you are allergic to any other substances including foods, preservatives, latex, or dyes. If you use a nebulizer to administer the medication, it should be cleaned immediately after use, since residues of the medicine can be sticky and may clog the apparatus. Nebulized solution may be inhaled directly from the nebulizer, or the nebulizer may be fitted with a plastic face mask or mouthpiece. When acetylcysteine is used by patients with asthma or other types of hypersensitivity of the airways, a bronchodilator should be administered first to prevent bronchospasm. Overdose SymptomsUnusual breathing difficulties. What to DoCall your doctor, emergency medical services (EMS), or local hospital immediately. Drug InteractionsSimultaneous use of acetylcysteine with tetracycline, erythromycin, lactobionate, amphotericin B, ampicillin, chymotrypsin, or hydrogen peroxide in the same solution should be avoided. Such medications should be taken at another time. Food InteractionsNo known food interactions. Disease InteractionsAcetylcysteine can aggravate asthma or other respiratory diseases. Serious Side EffectsWheezing, tightness in the chest, and breathing difficulty (especially among patients with asthma); spitting up of blood. Contact your doctor immediately if any such symptoms arise. Common Side EffectsAcetylcysteine does not commonly cause side effects. Less Common Side EffectsClammy skin, fever, increased mucus production in the lungs, pain or irritation around the mouth or throat, nausea and vomiting, runny nose, drowsiness. Such symptoms are likely to diminish as your body adjusts to the medication. | |
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