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Acetaminophen/Aspirin/Caffeine
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Acetaminophen/Aspirin/Caffeine In this Article:
Brand Name(s):Buffets II, Duradyne, Excedrin Extra-Strength, Excedrin Migraine, Gelpirin, Goody's Extra Strength Tablets, Goody's Headache Powders, Supac, Vanquish Caplets Drug Class:Analgesic Available OTC?:YesAvailable Generic?:No | |
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Available InTablets, caplets, oral powder Why PrescribedFor the temporary relief of mild to moderate pain associated with arthritis or migraine headache. How It WorksAcetaminophen and aspirin both appear to interfere with the production of prostaglandins, naturally occurring substances in the body that cause inflammation and make nerves more sensitive to pain impulses. Caffeine is believed to enhance the effectiveness of pain relievers. Range and FrequencyBecause the amount of each of the components varies with different brands, consult your doctor for the appropriate dose. The following are general guidelines. Adults and teenagers-- Tablets and caplets: 1 to 2 tablets or caplets every three to six hours, as needed and depending on the strength of the product. Do not take more than eight pills in a 24-hour period. If migraine pain persists for more than 48 hours or joint pain lasts for more than 10 days, stop taking the medication and call your doctor. Oral powder: 1 packet of powder followed immediately by a full glass of water every six hours. Children-- Tablets and caplets: Consult your pediatrician. Children should not take more than five pills in a 24-hour period. Oral powder: Not recommended for children. Onset of EffectUnknown. Duration of ActionUnknown. Dietary AdviceShould be taken with food or a full glass of water to minimize stomach upset. StorageStore in a tightly sealed container away from heat, moisture, and direct light. Missed DoseSkip the missed dose and then resume your regular dosage schedule. Do not double the next dose. Stopping the DrugYou may stop taking the drug whenever you choose. Prolonged UseThis combination is indicated for short-term use only. Side effects are more likely with prolonged use. Over 60Adverse reactions may be more likely and more severe. Driving and Hazardous WorkMay cause drowsiness or vision difficulties. AlcoholDo not consume more than two alcohol-containing beverages a day. PregnancyDiscuss with your doctor the relative risks and benefits of using this drug while pregnant. This drug should not be used during the last three months of pregnancy. Breast FeedingThis drug may pass into breast milk; consult your doctor for specific advice. Infants and ChildrenConsult your pediatrician. This drug should not be taken by children under 16, since the aspirin component may cause a very rare but life-threatening condition known as Reye's syndrome. Special ConcernsBe sure your doctor knows you are taking this medication; it can interfere with the results of some blood and urine tests. Patients allergic to aspirin should not take this medication. Overdose SymptomsNausea and vomiting, disorientation, seizures, rapid breathing, ringing or buzzing in the ears, fever, appetite loss, abdominal pain, excessive sweating, drowsiness or exhaustion, stomach tenderness, heartbeat irregularities, yellow discoloration of the skin and eyes, agitation, anxiety, excitement, restlessness, delirium. What to DoCall your doctor, emergency medical services (EMS), or the nearest poison control center immediately. Drug InteractionsConsult your doctor before taking this drug if you are currently taking any of the following: blood pressure medication, gout or arthritis drugs, anticoagulants such as warfarin, antidiabetic agents, steroids, seizure medication, NSAIDs, barbiturates, nicotine, zidovudine (AZT), isoniazid, any central nervous system stimulant, a MAO inhibitor, amantadine, over-the-counter cold and allergy medications, or asthma medicine. Food InteractionsDo not drink large amounts of caffeine-containing beverages like coffee, tea, cola, cocoa, or chocolate milk. Disease InteractionsConsult your doctor if you have liver or kidney disease, diabetes mellitus, phenylketonuria, a history of alcohol abuse, asthma, a bleeding disorder, congestive heart failure, gout, hemophilia, high blood pressure, thyroid disease, a peptic ulcer, anxiety, panic attacks, agoraphobia, or insomnia. Serious Side EffectsDifficulty swallowing; dizziness, lightheadedness, or fainting; flushing, redness, or change in color of skin; difficulty breathing, shortness of breath, tightness in the chest, or wheezing; sudden decrease in urine output; swelling of face, eyelids, or lips; black or tarry stools; unusual bleeding or bruising; yellow discoloration of the skin and eyes (indicating liver damage). Call your doctor immediately. Common Side EffectsIndigestion, nausea and vomiting, stomach pain. Less Common Side EffectsSleeping difficulty, nervousness, irritability. | |
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