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Acebutolol Hydrochloride
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Acebutolol Hydrochloride In this Article:
Brand Name(s):Sectral Drug Class:Beta-blocker Available OTC?:NoAvailable Generic?:Yes | |
| |  Sectral 200 mg (Wyeth-Ayerst) |
Available InCapsules Why PrescribedTo treat mild to moderate high blood pressure; also used to prevent or control heartbeat irregularities (cardiac arrhythmias). How It WorksAcebutolol slows the rate and force of contraction of the heart by blocking certain nerve impulses, thus reducing blood pressure. By modifying nerve impulses to the heart, the drug also helps to stabilize heart rhythm. Range and FrequencyAdults: Initially, 400 mg a day, either as a single dose in the morning or as two 200 mg doses taken in the morning and evening (12 hours apart). Maximum daily dose is 1,200 mg; for those over 65, daily dose should not exceed 800 mg. Onset of EffectOne to one and a half hours. Duration of ActionUp to 24 hours. Dietary AdviceFollow your doctor's dietary recommendations to improve control over high blood pressure and heart disease. StorageStore away from heat, moisture, and direct light. Missed DoseTake it as soon as you remember. If it is within four hours of the next scheduled dose, skip the missed dose and resume your regular dosage schedule. Do not double the next dose. Stopping the DrugSuddenly stopping acebutolol may cause blood pressure to rise (rebound) to high or even dangerous levels, possibly triggering angina or a heart attack in patients with advanced heart disease. Slow reduction of the dose over a period of two to three weeks is advised, under careful supervision by your doctor. Prolonged UseRegular visits to your doctor are needed to evaluate the drug's ongoing, long-term effectiveness. Over 60Many elderly patients are more sensitive to the drug than younger persons. Smaller doses and frequent blood pressure checks may be advised. Driving and Hazardous WorkUse caution until you determine how the medication affects you. AlcoholDrink in careful moderation, if at all. Alcohol may interact with the drug and cause a dangerous drop in blood pressure. PregnancyDiscuss with your doctor the relative risks and benefits of using this drug while pregnant. Breast FeedingTrace amounts of this drug can be found in breast milk, though adverse effects in infants have not been documented. Consult your doctor for advice. Infants and ChildrenNot recommended. Special ConcernsUse of the drug should be considered but one element of a comprehensive therapeutic program that includes weight control, smoking cessation, regular exercise, and a healthy low-salt, low-fat diet. Overdose SymptomsUnusually slow or rapid heartbeat, severe dizziness or fainting, poor circulation in the hands (bluish skin), breathing difficulty, seizures. What to DoContact your doctor immediately. Drug InteractionsConsult your doctor for specific advice if you are taking amphetamines, oral antidiabetic agents, asthma medication (such as aminophylline or theophylline), calcium channel blockers, clonidine, guanabenz, halothane, allergy shots, insulin, MAO inhibitors, reserpine, or other beta-blockers. Food InteractionsNone reported. Disease InteractionsAcebutolol should be used with caution in people with diabetes, especially insulin-dependent diabetes, since the drug may mask symptoms of hypoglycemia. Consult your doctor for specific advice if you have a history of allergies or asthma, heart or blood vessel disease (including congestive heart failure and peripheral vascular disease), hyperthyroidism, irregular (slow) heartbeat, myasthenia gravis, psoriasis, respiratory problems such as bronchitis or emphysema, kidney or liver disease, or mental depression. Serious Side EffectsSevere shortness of breath and rapid heartbeat (symptoms of congestive heart failure), worsening of asthma, severe allergic reaction (skin rash, itching, wheezing, swelling of lips, tongue, and throat). If any of these symptoms develop, seek medical attention immediately. Common Side EffectsCough, diarrhea, decreased sexual ability, depression, drowsiness, dizziness, fatigue, frequent urination, gas, indigestion, nausea, trouble sleeping, cold hands and feet, numbness or tingling in fingers or toes. Less Common Side EffectsFever, sore throat, abdominal pain, headache, anxiety, joint or back pain, dry or burning eyes, unusual bleeding or bruising, dark urine, nightmares or unusually vivid dreams. Drug/Nutrient Interactions | |
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